After opening as favorites, Rams are now 2.5-point underdogs vs. Bills

The Los Angeles Rams will play their opening game of

the 2022 season at home as the reigning Super Bowl champions.

The Rams were given the Super Bowl favourites in Week 1 by the NFL,

who could not have chosen a tougher opponent for their

opening matchup. Next Thursday, Sept. 8, the Rams will welcome

the Buffalo Bills at home. And even though the Rams began that

game as 0.5-point favourites when the schedule was unveiled, the line has significantly changed.

The Rams are a 2.5-point underdog against the Bills, per Tipico Sportsbook. It doesn't 

happen often that the defending champions are 2.5 point underdogs in Week 1. The game's over/under, which has been set at 52.5 points, is the second-highest of any next week.